The Lady Billies moved on to Thursday night's sectional final after blanking Van 10-0 in Wednesday night's opener at Man.
Sophomore all-state pitcher Marlena Frye tossed another no-hitter and junior Mercedes Sharp was a perfect 4-for-4 at the plate as the Lady Billies breezed.
Frye had 13 strikeouts and issued no walks. Sharp had a double and scored two runs.
The game was stopped after five innings due to the 10-run mercy rule.
Man got two runs in the bottom of the second and added five runs in the bottom of the third to take a 7-0 advantage. The Lady Billies never looked back as Man added one run in the fourth and two in the fifth to end the game early.
Van committed five errors to none for Man.
"We got good pitching and timely hitting," Lady Billies coach Randy Epperly said. "Sharp had a big game."
Kaitlan Chapman was 2-for-3 with two RBI for Man. Malorie Keffer was also 2-for-3 at the plate.
Tabby Johnston and Paige Stacy each had a hit and two RBI. Malorie Vance had a hit and two RBI.
Katie Bryant, Man's only senior on the roster, was 1-for-3 with a double and one RBI.
Wednesday night's contest was also Senior Night for the Lady Billies and Bryant was honored before the game.
In the first game of the night, Van routed Gilbert 16-5 in five innings.
Van plays Gilbert again in Thursday night's 5:30 p.m. elimination game.
The winner then takes on No. 2-ranked Man (18-3) in the finals at 7:30 p.m.
A victory by the favored Lady Billies puts Man into next week's Class A regional tourney.
Out of 18 wins this season Man has 13 shutouts and five games in which it allowed just one run.